1.Huang R, Ji X, Liang B, Jiang B, Wang D, Tang Y, Zhang C, Zhou A, Li N,Du C*, Sun Y. Integrated Genomic and Phenotypic Characterization of an Mcr-10.1-Harboring Multidrug Resistant Escherichia coli Strain From Migratory Birds in China. Transbound Emerg Dis. 2025 May 1; 2025:7631217.
2.Huang R, Gao W, Sun Y, Ye Y, Luo T, Pan Y, Zhang C, Zhou A, Ren W,Du C*. Genomic Characterization of Carbapenemase-Producing Klebsiella pneumoniae ST895 Isolates from Canine Origins Through Whole-Genome Sequencing Analysis. Microorganisms. 2025 Feb 3;13(2):332.
3.Huang R, Ji X, Zhu L, Zhang C, Luo T, Liang B, Jiang B, Zhou A,Du C*, Sun Y. Metagenomic and Antibiotic Resistance Analysis of the Gut Microbiota in Larus relictus and Anatidae Species Inhabiting the Honghaizi Wetland of Ordos, Inner Mongolia, from 2021 to 2023. Microorganisms. 2024 May 13;12(5):978.
4.Yu C, Zheng HH, Zhang YZ,Du CT*, Xie GH. Identification of canine mammary tumor-associated metabolites using untargeted metabolomics. Theriogenology. 2023 Nov;211:84-96.
5.Zheng HH, Yu C, Tang XY,Du CT*, Xie GH. Isolation, Identification and Antimicrobial Resistance Analysis of Canine Oral and Intestinal Escherichia coli Resistant to Colistin. Int J Mol Sci. 2023 Aug 30;24(17):13428.
6.Ma K, Chen W, Lin XQ, Liu ZZ, Wang T, Zhang JB, Zhang JG, Zhou CK, Gao Y,Du CT, Yang YJ. Culturing the Chicken Intestinal Microbiota and Potential Application as Probiotics Development. Int J Mol Sci. 2023 Feb 3;24(3):3045.
7.Zheng HH,Du CT, Zhang YZ, Yu C, Huang RL, Tang XY, Xie GH. A study on the correlation between intrauterine microbiota and uterine pyogenesis in dogs. Theriogenology. 2023 Jan 15;196:97-105.
8.Wang G, Liu H, Feng Y, Zhang Z, Hu H, Liu J, Qiu L, Guo Z, Huang J, Qiu J,Du C*. Colistin-resistance mcr genes in Klebsiella pneumoniae from companion animals. J Glob Antimicrob Resist. 2021 Mar 1;25:35-36. doi: 10.1016/j.jgar.2021.02.023. Epub ahead of print. PMID: 33662641.
9.Qinghe Han, Haiyu Wang, Chong Xiao, Ben-Dong Fu,Chong-Tao Du*. Oroxylin A inhibits H2O2-induced oxidative stress in PC12 cells. Nat Prod Res. 2017 Jun;31(11):1339-1342
10.Du C, Feng Y, Wang G, Zhang Z, Hu H, Yu Y, Liu J, Qiu L, Liu H, Guo Z, Huang J, Qiu J. Co-Occurrence of the mcr-1.1 and mcr-3.7 Genes in a Multidrug-Resistant Escherichia coli Isolate from China. Infection and Drug Resistance. 2020 Oct 19; 13: 3649-3655
11.Chong-Tao Du, Wei Gao, Ke Ma, Shui-Xing Yu, Na Li, Shi-Qing Yan, Feng-Hua Zhou, Zhen-Zhen Liu,Wei Chen, Lian-Cheng Lei, Yong-Jun Yang, Wen-Yu Han. MicroRNA146a Deficiency Protects against Listeria monocytogenes Infection by Modulating the Gut Microbiota. Int J Mol Sci. 2018 Mar 26;19(4)
12.Liu J, Zhang Z, Feng Y, Hu H, Yu Y, Qiu L, Liu H, Guo Z, Huang J,Du C*, Qiu J*. Molecular Detection of the mcr Genes by Multiplex PCR. Infection and Drug Resistance. 2020 Oct 12; 13: 3463-3468.
13.Liu Z, Wang J, Zhang Y, Wu D, Li S, Jiang A,Du C*, Xie G*. Pterostilbene Exerts Hepatoprotective Effects through Ameliorating LPS/D-Gal-Induced Acute Liver Injury in Mice. Inflammation. 2020 Oct 2
14.Hui-Hua Zheng*,Chong-Tao Du *, Yu-Zhu Zhang, Chao Yu, Rong-Lei Huang, Xin-Yue Tang, Guang-Hong Xie. A study on the correlation between intrauterine microbiota and uterine pyogenesis in dogs. Theriogenology. 2022 Nov 8;196:97-105.
15.Hui-Hua Zheng*,Chong-Tao Du *, Chao Yu, Xin-Yue Tang, Rong-Lei Huang, Yu-Zhu Zhang, Wei Gao and Guang-Hong Xie. The Relationship of Tumor Microbiome and Oral Bacteria and Intestinal Dysbiosis in Canine Mammary Tumor. Int J Mol Sci. 2022, 23(18), 10928
16.Hui-Hua Zheng*,Chong-Tao Du *, Yu-Zhu Zhang, Chao Yu, Rong-Lei Huang, Xin-Yue Tang, Guang-Hong Xie. Identification of Canine Pyometra-Associated Metabolites Using Untargeted Metabolomics. Int J Mol Sci. 2022 Nov 16;23(22):14161.
17.Shui-Xing Yu*,Chong-Tao Du*, Wei Chen, Qian-Qian Lei, Ning Li, Shuai Qi, Xiao-Jing Zhang, Gui-Qiu Hu, Xu-Ming Deng, Wen-Yu Han, Yong-Jun Yang. Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression.Sci Rep. 2015 Dec 11;5:17935
18.Zheng HH*,Du CT*, Yu C, Zhang YZ, Huang RL, Tang XY, Xie GH. Epidemiological Investigation of Canine Mammary Tumors in Mainland China Between 2017 and 2021. Front Vet Sci. 2022 Jun 22;9:843390.
19.Zheng H*,Du C*, Tang X, Zhang Y, Huang R, Yu C, Xie G. The development of molecular typing in canine mammary carcinomas. Mol Biol Rep. 2022 Jul 16.
20.Ma K, Chen W, Lin XQ, Liu ZZ, Wang T, Zhang JB, Zhang JG, Zhou CK, Gao Y,Du CT, Yang YJ. Culturing the Chicken Intestinal Microbiota and Potential Application as Probiotics Development. Int J Mol Sci. 2023 Feb 3;24(3):3045.
21.Gui-Qiu Hu, Yong-Jun Yang, Xiao-Xia Qin, Shuai Qi, Jie Zhang, Shui-Xing Yu,Chong-Tao Duand Wei Chen. Salmonella Outer Protein B Suppresses Colitis Development via Protecting Cell From Necroptosis. Front Cell Infect Microbiol. 2019 Apr 9; 9:87.
22.Zhang J, Qin D, Yang YJ, Hu GQ, Qin XX,Du CT, Chen W. MLKL deficiency inhibits DSS-induced colitis independent of intestinal microbiota. Mol Immunol. 2019 Mar;107:132-141.
23.Yu SX, Chen W, Hu XZ, Feng SY, Li KY, Qi S, Lei QQ, Hu GQ, Li N, Zhou FH, Ma CY,Du CT, Yang YJ. Liver X receptors agonists suppress NLRP3 inflammasome activation. Cytokine. 2017 Mar;91:30-37.
24.Li N, Fu Y, Chen W, Hu GQ, Zhou M, Yu SX, Zhang XJ,Du CT, Yang YJ. IFI16 mediates soluble Flt-1 and endoglin production by trophoblast cells. J Hypertens. 2015 Aug;33(8):1658-65.
25.Mei Yang,Chongtao Du, Pengjuan Gong, Feifei Xia, Changjiang Sun, Xin Feng, Liancheng Lei, Jun Song, Lei Zhang, Bin Wang, Feng Xiao, Xinwu Yan, Ziyin Cui, Xinwei Li, Jingmin Gu, Wenyu Han . Therapeutic effect of the YH6 phage in a murine hemorrhagic pneumonia model. Res Microbiol. 2015 Oct; 166(8):633-43.
26.Feng S, Yang Y, Liu Z, Chen W,Du C, Hu G, Yu S, Song P, Miao J. Intracellular bacteriolysis contributes to pathogenicity of Staphylococcus aureus by exacerbating AIM2-mediated inflammation and necroptosis. Virulence. 2022 Dec;13(1):1684-1696.
27.Xiao J, Liu J, Bao C, Zhu R, Gu J, Sun C, Feng X,Du C, Han W, Li Y, Lei L. Recombinant tandem epitope vaccination provides cross protection against Actinobacillus pleuropneumoniae challenge in mice. AMB Express. 2020 Jul 8;10(1):123.
28.Wang S, Yin B, Yu L, Dang M, Guo Z, Yan G, Hu D, Gu J,Du C, Feng X, Han W, Adam YY, Sun C, Bossé JT, Lei L. Overexpression of AmpC Promotes Bacteriophage Lysis of Ampicillin-Resistant Escherichia coli. Front Microbiol. 2020 Jan 8;10:2973.
29.Yu SX, Chen W, Liu ZZ, Zhou FH, Yan SQ, Hu GQ, Qin XX, Zhang J, Ma K,Du CT, Gu JM, Deng XM, Han WY, Yang YJ. Non-Hematopoietic MLKL Protects Against Salmonella Mucosal Infection by Enhancing Inflammasome Activation. Front Immunol. 2018 Feb 2;9:119.
30.Yu L, Wang S, Guo Z, Liu H, Sun D, Yan G, Hu D, Du C, Feng X, Han W, Gu J, Sun C, Lei L. A guard-killer phage cocktail effectively lyses the host and inhibits the development of phage-resistant strains of Escherichia coli. Appl Microbiol Biotechnol. 2018 Jan;102(2):971-983.
31.Hu GQ, Song PX, Chen W, Qi S, Yu SX, Du CT, Deng XM, Ouyang HS, Yang YJ. Cirtical role for Salmonella effector SopB in regulating inflammasome activation. Mol Immunol. 2017 Oct;90:280-286.
32.Yu SX, Zhou FH, Chen W, Jiang GM,Du CT, Hu GQ, Liu ZZ, Yan SQ, Gu JM, Deng XM, Lin TJ, Duan EK, Yang YJ. Decidual Stromal Cell Necroptosis Contributes to Polyinosinic-Polycytidylic Acid-Triggered Abnormal Murine Pregnancy. Front Immunol. 2017 Aug 2;8:916.
33.Liu J, Ma Q, Yang F, Zhu R, Gu J, Sun C, Feng X, Du C, Langford PR, Han W, Yang J, Lei L. B cell cross-epitope of Propionibacterium acnes and Actinobacillus pleuropneumonia selected by phage display library can efficiently protect from Actinobacillus pleuropneumonia infection. Vet Microbiol. 2017 Jun;205:14-21.
34.Sheng X, You Q, Zhu H, Chang Z, Li Q, Wang H, Wang C, Wang H, Hui L,Du C, Xie X, Zeng R, Lin A, Shi D, Ruan K, Yan J, Gao GF, Shao F, Hu R. Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK. PLoS Pathog. 2017 Jul 28;13(7):e1006534
35.Wang S, Gu J, Lv M, Guo Z, Yan G, Yu L, Du C, Feng X, Han W, Sun C, Lei L. The antibacterial activity of E. coli bacteriophage lysin lysep3 is enhanced by fusing the Bacillus amyloliquefaciens bacteriophage endolysin binding domain D8 to the C-terminal region. J Microbiol. 2017 May;55(5):403-408.
36.Qin W, Wang L, Zhai R, Ma Q, Liu J, Bao C, Sun D, Zhang H, Sun C, Feng X, Gu J, Du C, Han W, Langford PR, Lei L. Apa2H1, the first head domain of Apa2 trimeric autotransporter adhesin, activates mouse bone marrow-derived dendritic cells and immunization with Apa2H1 protects against Actinobacillus pleuropneumoniae infection. Mol Immunol. 2017 Jan;81:108-117.
37.Lei QQ, Hu GQ, Chen W, Yu SX, Qi S, Du CT, Gu JM, Lin TJ, Yang YJ. RCAN1 deficiency protects against Salmonella intestinal infection by modulating JNK activation. Mol Immunol. 2016 Sep;77:26-33.
38.Hu GQ, Song PX, Li N, Chen W, Lei QQ, Yu SX, Zhang XJ,Du CT, Deng XM, Han WY, Yang YJ. AIM2 contributes to the maintenance of intestinal integrity via Akt and protects against Salmonella mucosal infection. Mucosal Immunol. 2016 Sep; 9(5):1330-9
39.Wang L, Qin W, Zhang J, Bao C, Zhang H, Che Y, Sun C, Gu J, Feng X, Du C, Han W, Richard PL, Lei L. Adh enhances Actinobacillus pleuropneumoniae pathogenicity by binding to OR5M11 and activating p38 which induces apoptosis of PAMs and IL-8 release. Sci Rep. 2016 Apr 5;6:24058.
40.Sun Y, Li N, Zhang J, Liu H, Liu J, Xia X, Sun C, Feng X, Gu J, Du C, Han W, Lei L. Enolase of Streptococcus Suis Serotype 2 Enhances Blood-Brain Barrier Permeability by Inducing IL-8 Release. Inflammation. 2016 Apr;39(2):718-26.
41.Wang L, Qin W, Yang S, Zhai R, Zhou L, Sun C, Pan F, Ji Q, Wang Y, Gu J, Feng X, Du C, Han W, Langford PR, Lei L. The Adh adhesin domain is required for trimeric autotransporter Apa1-mediated Actinobacillus pleuropneumoniae adhesion, autoaggregation, biofilm formation and pathogenicity. Vet Microbiol. 2015 May 15;177(1-2):175-83.
42.Ma Q, Sun C, Yang F, Wang L, Qin W, Xia X, Feng X, Du C, Gu J, Han W, Lei L. Macrophages largely contribute to heterologous anti-Propionibacterium acnes antibody-mediated protection from Actinobacillus pleuropneumoniae infection in mice. Microbiol Immunol. 2015 Mar;59(3):166-73.
43.Chu X, Chen W, Li N, Hu XZ,Du CT, Yu SX, Zhou M, Zhang XJ, Jiang GM, Han WY, Deng XM, Yang YJ. Cytosolic double-stranded DNA induces nonnecroptotic programmed cell death in trophoblasts via IFI16. J Infect Dis. 2014 Nov 1;210(9):1476-86
44.Gu J, Feng Y, Feng X, Sun C, Lei L, Ding W, Niu F, Jiao L, Yang M, Li Y, Liu X, Song J, Cui Z, Han D,Du C, Yang Y, Ouyang S, Liu ZJ, Han W. Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysin. PLoS Pathog. 2014 May 15;10(5):e1004109
45.Liu Q, Han W, Sun C, Zhou L, Ma L, Lei L, Yan S, Liu S,Du C, Feng X. Deep sequencing-based expression transcriptional profiling changes during Brucella infection. Microb Pathog. 2012 May;52(5):267-77
46.Xie F, Lei L,Du C, Li S, Han W, Ren Z. Genomic differences between Actinobacillus pleuropneumoniae serotypes 1 and 3 and the diversity distribution among 15 serotypes. FEMS Microbiol Lett. 2010 Feb;303(2):147-55.
47.杜崇涛,张晓静,杨梅,刘宏涛,冯世源,韩文瑜.非编码RNA在胞内病原菌免疫逃逸与致病中的作用[J].生命科学,2014,26(09):897-902.（国家自然基金“双清论坛”邀请综述）
获得授权专利11项，以下为代表性专利
1.雷连成,杜崇涛, et al.一种合成三聚氰胺完全抗原的方法及检测三聚氰胺的ELISA试剂盒，ZL200810051488.5
2.雷连成,杜崇涛, et al.利用抗菌肽制备细菌菌影的方法及应用，ZL200910067286.4
3.雷连成,杜崇涛, et al.联合利用抗菌肽和超高压制备细菌菌影的方法及应用，ZL200910067287.9
标准
实验用猫免疫操作技术规范，吉林省地方标准
